Not known Factual Statements About sodium pentobarbital
Not known Factual Statements About sodium pentobarbital
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pentobarbital decreases effects of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Coadministration of CYP3A4 inducers might lower sufentanil concentrations and efficacy, quite possibly precipitating withdrawal syndrome in patients that have produced physical dependence to sufentanil. Discontinuation of concomitantly used CYP3A4 inducers may possibly raise sufentanil plasma concentration.
pentobarbital will lessen the extent or effect of osilodrostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
buprenorphine subdermal implant and pentobarbital the two maximize sedation. Stay away from or Use Alternate Drug. Restrict use to people for whom alternative therapy selections are insufficient
pentobarbital will decrease the extent or effect of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Effect of coadministering a solid CYP3A4 inducer with fedratinib has not been examined.
pentobarbital will decrease the extent or effect of pimavanserin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Prevent coadministration if at all possible. Keep an eye on for diminished pimavanserin efficacy. A rise in pimavanserin dosage can be wanted.
pentobarbital will decrease the level or effect of estradiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lessen the level or effect of triamcinolone acetonide injectable suspension by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the level or effect of parecoxib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
pentobarbital will reduce the level or effect of amiodarone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will reduce the level or effect of efavirenz by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.
pentobarbital will reduce the level or effect of ramelteon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Mysterious.
pentobarbital will lower the extent or effect of zonisamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
Having said that, the use of barbiturates as sedatives during the postoperative surgical interval and as check here adjuncts to most cancers chemotherapy is properly founded.
pentobarbital will reduce the level or effect of vardenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.